Description

1H-Indole-6-Carbonitrile, 3-(2-Aminoethyl)- is a high-value, multi-functional indole derivative with a reactive carbonitrile group and a primary amine side chain. This unique bifunctional structure makes it a critical advanced pharmaceutical intermediate for the synthesis of complex bioactive molecules. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in the areas of neurology and oncology.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new generation pesticides and plant growth regulators.
• Biochemical Probe Synthesis: Serves as a precursor for creating labeled compounds and molecular probes for biological research.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1H-Indole-6-Carbonitrile, 3-(2-Aminoethyl)-
CAS No.	467451-88-3
Molecular Formula	C11H11N3
Molecular Weight	185.23 g/mol
Synonyms	3-(2-Aminoethyl)-1H-indole-6-carbonitrile; 6-Cyano-3-(2-aminoethyl)indole; 3-(2-Aminoethyl)indole-6-carbonitrile; 2-(6-Cyano-1H-indol-3-yl)ethan-1-amine; Tryptamine-6-carbonitrile; 6-Cyanotryptamine
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole-6-Carbonitrile, 3-(2-Aminoethyl)- is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Our products undergo rigorous quality testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatograms and spectral data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the material under an inert atmosphere or in a desiccator for long-term preservation. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.