Description

3-(Bromomethyl)Cyclobutanone is a versatile and reactive brominated cyclobutanone derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its unique strained-ring structure and the reactive bromomethyl handle, enabling efficient carbon-carbon bond formation and ring-expansion reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially those containing cyclobutane or spirocyclic ring systems with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require the incorporation of a functionalized cyclobutane moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of monomers and polymers with unique thermal or mechanical properties derived from the strained cyclobutane ring.
• Chemical Biology Probes: Useful for constructing molecular probes and tags due to its reactive bromomethyl group, which can be used for bioconjugation.
• Academic & Process Chemistry: A valuable reagent for methodological studies in ring-opening, cross-coupling, and annulation reactions in academic and industrial R&D settings.

Basic Information

Product Name	3-(Bromomethyl)Cyclobutanone
CAS No.	463961-43-5
Molecular Formula	C5H7BrO
Molecular Weight	163.01 g/mol
Synonyms	3-(Bromomethyl)cyclobutan-1-one; Cyclobutanone, 3-(bromomethyl)-; 3-Bromomethylcyclobutanone; (3-Bromomethyl)cyclobutanone; Bromomethyl cyclobutanone
EINECS	Contact for details

Quality Control

Our 3-(Bromomethyl)Cyclobutanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.