Description

n-Boc-Thiazolidine-Carboxylic Acid Dmap Salt is a high-purity, protected amino acid derivative primarily used as a critical building block in advanced organic synthesis. This compound matters because it offers a stable, activated form of the thiazolidine carboxylic acid moiety, facilitating efficient peptide coupling and complex molecule assembly under mild conditions. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of novel active pharmaceutical ingredients (APIs), peptide-based therapeutics, and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing thiazolidine or proline-like structures.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected and activated amino acid derivative to incorporate the thiazolidine-4-carboxylic acid residue.
• Protease Inhibitor Development: Serves as a core scaffold or building block for designing inhibitors targeting various proteases.
• Chemical Biology & Probe Development: Employed in the creation of chemical probes and bioconjugates for studying biological pathways and protein function.
• Material Science Research: Utilized in the synthesis of novel polymers or functional materials with specific chiral or structural properties.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	n-Boc-Thiazolidine-Carboxylic Acid Dmap Salt
CAS No.	462101-64-0
Molecular Formula	C15H22N2O5S
Molecular Weight	342.41 g/mol
Synonyms	1,1-Dimethylethyl (4R)-2,3-dihydro-1,3-thiazole-4-carboxylate 1-oxide compound with 4-(dimethylamino)pyridine (1:1); tert-Butyl (R)-thiazolidine-4-carboxylate 1-oxide 4-dimethylaminopyridine salt; Boc-Thiazolidine-4-carboxylic acid DMAP salt; (R)-1-(tert-Butoxycarbonyl)thiazolidine-4-carboxylic acid DMAP salt; N-Boc-L-thiazolidine-4-carboxylic acid DMAP salt; (R)-N-Boc-thiazolidine-4-carboxylic acid 4-dimethylaminopyridine salt; Protected thiazolidine carboxylic acid DMAP salt; Boc-Thz-OH•DMAP
EINECS	Contact for details

Quality Control

Our n-Boc-Thiazolidine-Carboxylic Acid Dmap Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and specific tests is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.