Description

Ethyl 4-(3-Aminophenyl)Thiazole-2-Carboxylate is a high-purity, functionalized thiazole derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino group and an ester moiety, makes it a versatile intermediate for constructing complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole core.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: A versatile building block for constructing more complex heterocycles, such as fused thiazole systems, via its reactive amino and ester functional groups.
• Dye and Pigment Industry: Intermediate for synthesizing specialized dyes and optical brighteners due to its conjugated aromatic-thiazole structure.

Basic Information

Product Name	Ethyl 4-(3-Aminophenyl)Thiazole-2-Carboxylate
CAS No.	460750-28-1
Molecular Formula	C12H12N2O2S
Molecular Weight	248.30 g/mol
Synonyms	Ethyl 4-(3-aminophenyl)-1,3-thiazole-2-carboxylate; 2-Thiazolecarboxylic acid, 4-(3-aminophenyl)-, ethyl ester; 4-(3-Aminophenyl)thiazole-2-carboxylic acid ethyl ester; 3-Amino-4-phenylthiazole-2-carboxylate ethyl ester; ATCE; 460750-28-1; Ethyl 4-(m-aminophenyl)thiazole-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4-(3-Aminophenyl)Thiazole-2-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.