Description

4-(3-Hydroxy-Propylamino)-1,1-Dioxo-Tetrahydro-1-Thiophen-3-Ol is a high-purity, specialized organic compound featuring a unique sulfolane-derived structure with both amino and hydroxyl functional groups. This molecular architecture makes it a valuable advanced intermediate for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by pharmaceutical R&D and custom synthesis organizations for developing novel therapeutic agents and high-value specialty products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system or metabolic diseases.
• Chiral Synthesis: Utilized in the preparation of enantiomerically pure compounds due to its potential for introducing stereogenic centers.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Bioconjugation Chemistry: Its functional groups make it suitable for linking molecules in probe or drug conjugate development.
• Advanced Material Research: Investigated as a monomer or additive for specialty polymers with specific solubility or electronic properties.
• Agrochemical Synthesis: Used in research for developing new generation crop protection agents with novel modes of action.

Basic Information

Item	Detail
Product Name	4-(3-Hydroxy-Propylamino)-1,1-Dioxo-Tetrahydro-1-Thiophen-3-Ol
CAS No.	459413-88-8
Molecular Formula	C7H15NO4S
Molecular Weight	209.26 g/mol
Synonyms	3-Hydroxy-4-(3-hydroxypropylamino)tetrahydrothiophene 1,1-dioxide; Tetrahydro-3-hydroxy-4-[(3-hydroxypropyl)amino]thiophene 1,1-dioxide; 4-[(3-Hydroxypropyl)amino]-3-hydroxytetrahydrothiophene 1,1-dioxide; 3-Hydroxy-4-(3-hydroxypropylamino)thiolane 1,1-dioxide; 4-(3-Hydroxy-propylamino)-tetrahydro-thiophene-3-ol-1,1-dioxide; 459413-88-8; Amino-hydroxy sulfolane derivative
EINECS	Contact for details

Quality Control

Every batch of 4-(3-Hydroxy-Propylamino)-1,1-Dioxo-Tetrahydro-1-Thiophen-3-Ol is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot, supporting regulatory submissions and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.