Description

3-Oxabicyclo[3.1.0]Hexan-2-One,4-Ethyl-1-Phenyl-,(1S,4S,5R)-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique fused bicyclic lactone structure makes it a valuable intermediate for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where stereochemistry is critical for biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the creation of enantiomerically pure pesticides and herbicides, where the specific stereochemistry can enhance efficacy and reduce environmental impact.
• Asymmetric Catalysis Ligand Precursor: The rigid bicyclic framework can be modified to develop novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or precursor for synthesizing polymers with specific optical or mechanical properties.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for complex organic molecules.

Basic Information

Item	Details
Product Name	3-Oxabicyclo[3.1.0]Hexan-2-One,4-Ethyl-1-Phenyl-,(1S,4S,5R)-(9Ci)
CAS No.	459143-17-0
Molecular Formula	C13H14O2
Molecular Weight	202.25 g/mol
Synonyms	(1S,4S,5R)-4-Ethyl-1-phenyl-3-oxabicyclo[3.1.0]hexan-2-one; 4-Ethyl-1-phenyl-3-oxabicyclo[3.1.0]hexan-2-one, (1S,4S,5R)-; (-)-(1S,4S,5R)-4-Ethyl-1-phenyl-3-oxabicyclo[3.1.0]hexan-2-one; Chiral bicyclic lactone; 459143-17-0; 3-Oxabicyclo[3.1.0]hexane-2-one, 4-ethyl-1-phenyl-, (1S,4S,5R)-
EINECS	Contact for details

Quality Control

Every batch of 3-Oxabicyclo[3.1.0]Hexan-2-One,4-Ethyl-1-Phenyl-,(1S,4S,5R)-(9Ci) is produced and controlled under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.