Description

3-Iodo-5-Nitro-1H-Indazole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for complex organic synthesis. This compound is valued for its role as a versatile building block in medicinal chemistry, particularly for constructing indazole-based scaffolds. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel indazole-containing drug candidates, particularly in oncology and CNS research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of complex molecular libraries.
• Agrochemical Development: Potential application in the research and synthesis of new crop protection agents and pesticides.
• Material Science: Investigated as a monomer or specialty additive in the development of advanced functional materials.

Basic Information

Product Name	3-Iodo-5-Nitro-1H-Indazole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	459133-69-8
Molecular Formula	C₁₂H₁₂IN₃O₄
Molecular Weight	389.15 g/mol
Synonyms	tert-Butyl 3-iodo-5-nitro-1H-indazole-1-carboxylate; 1H-Indazole-1-carboxylic acid, 3-iodo-5-nitro-, 1,1-dimethylethyl ester; 3-Iodo-5-nitro-1H-indazole-1-carboxylic acid 1,1-dimethylethyl ester; 459133-69-8; tert-Butyl 3-iodo-5-nitroindazole-1-carboxylate; BOC-protected 3-iodo-5-nitroindazole
EINECS	Contact for details

Quality Control

Our 3-Iodo-5-Nitro-1H-Indazole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.