Description

Bicyclo[2.2.1]Heptane-1-Carboxamide, n-Hydroxy-7,7-Dimethyl-2-Oxo-, (1S,4R)- (9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including enzyme inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or precursor for designing and synthesizing novel drug candidates with specific stereochemistry.
• Enzyme Inhibitor Synthesis: Serves as a building block for creating potent and selective enzyme inhibitors, leveraging its hydroxamic acid moiety.
• Chemical Biology Probes: Employed in the development of chemical probes to study biological pathways and target validation.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of complex target molecules.
• Academic Research: Utilized in university and institutional labs for synthetic methodology development and bioorganic studies.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-1-Carboxamide, n-Hydroxy-7,7-Dimethyl-2-Oxo-, (1S,4R)- (9Ci)
CAS No.	459124-75-5
Molecular Formula	C10H15NO3
Molecular Weight	197.23 g/mol
Synonyms	(1S,4R)-N-Hydroxy-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide; (1S,4R)-7,7-Dimethyl-2-oxo-N-hydroxybicyclo[2.2.1]heptane-1-carboxamide; endo-N-Hydroxy-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide; Bicyclo[2.2.1]heptane-1-carboxamide, N-hydroxy-7,7-dimethyl-2-oxo-, (1S,4R)-; 459124-75-5; (1S,4R)-HONB; A chiral hydroxamic acid derivative.
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-1-Carboxamide, n-Hydroxy-7,7-Dimethyl-2-Oxo-, (1S,4R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere to prevent oxidation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.