Description

3-Bromopyridin-4-Ylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex pyridine-based structures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for studying biological systems.
• Library Synthesis for High-Throughput Screening: A valuable reagent for medicinal chemistry teams constructing diverse compound libraries to identify new biological hits.
• Catalyst & Ligand Development: Used to synthesize novel bidentate or tridentate ligands for transition metal catalysis.

Basic Information

Product Name	3-Bromopyridin-4-Ylboronic Acid
CAS No.	458532-99-5
Molecular Formula	C5H5BBrNO2
Molecular Weight	201.82 g/mol
Synonyms	(3-Bromopyridin-4-yl)boronic Acid; 3-Bromo-4-pyridineboronic Acid; 4-Borono-3-bromopyridine; 3-Bromo-4-pyridinylboronic Acid; 3-Bromo-4-pyridylboronic Acid; B-(3-Bromo-4-pyridinyl)boronic Acid; 458532-99-5 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 3-Bromopyridin-4-Ylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), identity confirmation (NMR, IR), and impurity profile is supplied with each shipment to guarantee reproducible performance and supply chain reliability for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and potentially air/moisture-sensitive nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.