Description

8-Azabicyclo[3.2.1]Octane-2,3,4-Triol, (1R,2S,3-Exo,4R,5S)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic amino alcohol derivative, serving as a critical chiral building block and synthetic intermediate. Its value lies in providing a rigid, functionalized scaffold essential for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for developing active pharmaceutical ingredients (APIs), particularly in areas like neurology and antiviral research, where its specific stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Utilized as a building block or chiral auxiliary in stereoselective organic synthesis to induce specific stereochemistry.
• Neurological Drug Research: Investigated for its potential as a core structure in compounds targeting neurological pathways and receptors.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Chemical Biology Probes: Used to develop molecular probes for studying enzyme mechanisms or protein interactions due to its functional group array.
• Fine Chemical Production: Serves as a precursor for the synthesis of more complex, high-value specialty chemicals and catalysts.

Basic Information

Product Name	8-Azabicyclo[3.2.1]Octane-2,3,4-Triol, (1R,2S,3-Exo,4R,5S)-Rel- (9Ci)
CAS No.	455325-05-0
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(1R,2S,3R,4R,5S)-8-Azabicyclo[3.2.1]octane-2,3,4-triol; rel-(1R,2S,3-exo,4R,5S)-8-Azabicyclo[3.2.1]octane-2,3,4-triol; 8-Azabicyclo[3.2.1]octane-2,3,4-triol, (1R,2S,3-exo,4R,5S)-rel-; 455325-05-0; Bicyclic amino triol; Nortropane triol derivative; Chiral azabicyclooctane triol
EINECS	Contact for details

Quality Control

Our 8-Azabicyclo[3.2.1]Octane-2,3,4-Triol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet exacting customer specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.