Description

8-Azabicyclo[3.2.1]Octane-2,3,6-Triol, (1S,2R,3R,5S,6R)- (9Ci) is a high-purity, stereochemically defined bicyclic amino alcohol derivative, serving as a critical chiral building block and advanced pharmaceutical intermediate. Its precise stereochemistry and functional group arrangement make it invaluable for the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. This compound is essential for research and development laboratories and production facilities focused on creating novel therapeutics, including alkaloid analogs and other nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of active pharmaceutical ingredients (APIs), especially in the development of tropane alkaloid derivatives and other neurologically active compounds.
• Medicinal Chemistry Research: Used as a versatile scaffold in drug discovery programs for constructing libraries of compounds with potential therapeutic activity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and enzyme functions.
• Academic & Institutional Research: Utilized in universities and research institutes for synthetic organic chemistry studies and methodology development.
• Fine Chemical Synthesis: A building block for the multi-step synthesis of complex natural products and specialty fine chemicals.

Basic Information

Product Name	8-Azabicyclo[3.2.1]Octane-2,3,6-Triol, (1S,2R,3R,5S,6R)- (9Ci)
CAS No.	455325-03-8
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(1S,2R,3R,5S,6R)-8-Azabicyclo[3.2.1]octane-2,3,6-triol; (1S,2R,3R,5S,6R)-2,3,6-Trihydroxy-8-azabicyclo[3.2.1]octane; 8-Azabicyclo[3.2.1]octane-2,3,6-triol, (1α,2β,3α,5α,6β)-; 8-Azabicyclo[3.2.1]octane-2,3,6-triol, (1S,2R,3R,5S,6R)-rel-; 455325-03-8; 8-Azabicyclo[3.2.1]octane-2,3,6-triol stereoisomer
EINECS	Contact for details

Quality Control

Our 8-Azabicyclo[3.2.1]Octane-2,3,6-Triol, (1S,2R,3R,5S,6R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic confirmation (NMR, MS) are provided to guarantee batch-to-batch consistency and identity.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. For long-term stability, storage at 2-8°C is recommended. Keep the container tightly sealed in a dry environment to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.