Description

5-Bromopyridine-3-Boronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to construct complex heterocyclic architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with tailored biological activity.
• Material Science & OLED Development: Building block for creating organic light-emitting diode (OLED) materials, liquid crystals, and conductive polymers.
• Ligand & Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and inhibitors for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Bromopyridine-3-Boronic Acid
CAS No.	452972-09-7
Molecular Formula	C5H5BBrNO2
Molecular Weight	201.82 g/mol
Synonyms	(5-Bromopyridin-3-yl)boronic Acid; 3-Borono-5-bromopyridine; 5-Bromo-3-pyridineboronic Acid; 5-Bromo-3-pyridinylboronic Acid; 5-Bromonicotinylboronic Acid; 5-Bromo-3-pyridylboronic Acid; B-(5-Bromo-3-pyridinyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 5-Bromopyridine-3-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.