Description

5-(2-Chloro-Acetylamino)-4-Cyano-3-Methyl-Thiophene-2-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its molecular architecture, featuring a thiophene core with chloroacetyl, cyano, and ester functionalities, makes it a versatile precursor for constructing complex pharmacophores and agrochemical intermediates. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a crucial building block in the research and production of advanced pesticides, herbicides, and fungicides.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic compounds and exploring new chemical reactions.
• Material Science Precursor: Potential application in the synthesis of specialty chemicals and functional materials requiring specific thiophene-based structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects.

Basic Information

Product Name	5-(2-Chloro-Acetylamino)-4-Cyano-3-Methyl-Thiophene-2-Carboxylic Acid Ethyl Ester
CAS No.	449177-08-6
Molecular Formula	C12H11ClN2O3S
Molecular Weight	298.74 g/mol
Synonyms	Ethyl 5-[(2-chloroacetyl)amino]-4-cyano-3-methylthiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 5-[(2-chloroacetyl)amino]-4-cyano-3-methyl-, ethyl ester; 449177-08-6; 5-(2-Chloroacetamido)-4-cyano-3-methylthiophene-2-carboxylic acid ethyl ester; Ethyl 5-(2-chloroacetamido)-4-cyano-3-methylthiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 5-(2-Chloro-Acetylamino)-4-Cyano-3-Methyl-Thiophene-2-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The compound may be moisture-sensitive; ensure containers are sealed properly after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.