Description

1-Methyl-3-(1-Methylpiperidin-4-Yl)-1H-Indol-5-Yl 2,6-Difluorobenzenesulfonate is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound is valued for its complex heterocyclic structure, which serves as a critical building block for the synthesis of novel bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent, investigational drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities with improved efficacy and safety profiles.
• Oncology Drug Development: Serves as a core scaffold for compounds being evaluated in preclinical and clinical research for anti-cancer activity.
• CNS-Targeted Therapeutics: Employed in the research and development of potential treatments for neurological and psychiatric conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Biochemical Tool Compound: May be utilized in vitro as a pharmacological probe to study specific enzyme or receptor interactions in biological assays.

Basic Information

Product Name	1-Methyl-3-(1-Methylpiperidin-4-Yl)-1H-Indol-5-Yl 2,6-Difluorobenzenesulfonate
CAS No.	445441-26-9
Molecular Formula	C21H22F2N2O3S
Molecular Weight	420.47 g/mol
Synonyms	5-Indolol, 1-methyl-3-(1-methyl-4-piperidinyl)-, 2,6-difluorobenzenesulfonate (ester); 1-Methyl-3-(1-methylpiperidin-4-yl)-1H-indol-5-yl 2,6-difluorobenzenesulfonate; 445441-26-9; UNII-4Q7Q8K9Q3C; 4Q7Q8K9Q3C; 1-Methyl-3-(1-methyl-4-piperidinyl)-1H-indol-5-ol 2,6-difluorobenzenesulfonate; Benzenesulfonic acid, 2,6-difluoro-, 1-methyl-3-(1-methyl-4-piperidinyl)-1H-indol-5-yl ester
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-(1-Methylpiperidin-4-Yl)-1H-Indol-5-Yl 2,6-Difluorobenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The material should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.