Description

2-Thiophenecarboxylicacid,3-(Aminomethyl)-,Ethylester(9Ci) is a high-purity, functionalized thiophene derivative with significant synthetic utility. This compound matters as a versatile and critical building block in advanced organic synthesis, particularly for constructing complex heterocyclic scaffolds. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients. Its unique structure, combining a thiophene core with ester and aminomethyl functionalities, makes it a valuable intermediate for creating molecules with tailored biological and material properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science Research: Serves as a precursor for functionalized monomers in the development of conductive polymers, organic semiconductors, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or linker for designing chemical probes, enzyme inhibitors, and bioconjugation reagents.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D.
• Academic & Institutional Research: Used in university and government laboratories for fundamental studies in heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	2-Thiophenecarboxylicacid,3-(Aminomethyl)-,Ethylester(9Ci)
CAS No.	445391-62-8
Molecular Formula	C9H11NO2S
Molecular Weight	197.25 g/mol
Synonyms	Ethyl 3-(aminomethyl)thiophene-2-carboxylate; 3-(Aminomethyl)thiophene-2-carboxylic Acid Ethyl Ester; 2-Thiophenecarboxylic acid, 3-(aminomethyl)-, ethyl ester; Ethyl 3-aminomethylthiophene-2-carboxylate; 3-Carbamoylmethyl-thiophene-2-carboxylic acid ethyl ester (related); Aminomethylthiophene ethyl ester; Thiophene-2-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxylicacid,3-(Aminomethyl)-,Ethylester(9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.