Description

Ethyl 4-Chlorothiazole-5-Carboxylate is a high-value heterocyclic building block and key pharmaceutical intermediate. This compound is essential for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel thiazole-based scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that incorporate the thiazole moiety for enhanced bioactivity.
• Material Science Research: Serves as a building block for creating functionalized thiazoles used in organic electronics, such as OLED materials and conductive polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and enzyme inhibitors for target validation and mechanistic studies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up campaigns in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	Ethyl 4-Chlorothiazole-5-Carboxylate
CAS No.	444909-55-1
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.64 g/mol
Synonyms	Ethyl 4-chloro-1,3-thiazole-5-carboxylate; 4-Chloro-thiazole-5-carboxylic acid ethyl ester; 5-Carbethoxy-4-chlorothiazole; 4-Chloro-5-ethoxycarbonylthiazole; 4-Chloro-5-thiazolecarboxylic acid, ethyl ester; Ethyl 4-chloro-5-thiazolecarboxylate; 1,3-Thiazole-5-carboxylic acid, 4-chloro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chlorothiazole-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.