Description

Cyclopropanecarboxylic Acid (7-Oxo-6,7-Dihydro-5H-Indeno[5,6-D][1,3]Dioxol-5-Yl)-Amide is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused-ring indanone-dioxole structure. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, especially for central nervous system (CNS) and anti-inflammatory targets.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates and novel APIs.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	Cyclopropanecarboxylic Acid (7-Oxo-6,7-Dihydro-5H-Indeno[5,6-D][1,3]Dioxol-5-Yl)-Amide
CAS No.	444151-83-1
Molecular Formula	C15H13NO4
Molecular Weight	271.27 g/mol
Synonyms	5H-Indeno[5,6-d][1,3]dioxol-5-amine, N-(cyclopropylcarbonyl)-7-oxo-6,7-dihydro-; (7-Oxo-6,7-dihydro-5H-indeno[5,6-d][1,3]dioxol-5-yl)cyclopropanecarboxamide; Cyclopropanecarboxamide, N-(7-oxo-6,7-dihydro-5H-indeno[5,6-d][1,3]dioxol-5-yl)-; 444151-83-1; Advanced Indanone-Dioxole Intermediate; Pharmaceutical Building Block 444151-83-1
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid (7-Oxo-6,7-Dihydro-5H-Indeno[5,6-D][1,3]Dioxol-5-Yl)-Amide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.