Description

n-[4-({[4-(Aminosulfonyl)Phenyl]Amino}Sulfonyl)Phenyl]-3-Chloro-1-Benzothiophene-2-Carboxamide CAS NO 444151-61-5 is a high-purity, synthetic organic compound featuring a benzothiophene core functionalized with chloro, carboxamide, and dual sulfonamide groups. This complex molecular architecture makes it a valuable advanced pharmaceutical intermediate and a critical building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in developing novel therapeutic agents, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and library synthesis.
• Protease Inhibitor Development: The sulfonamide and benzothiophene motifs suggest potential application in designing enzyme inhibitors.
• Kinase Inhibitor Synthesis: Employed in the research and development of targeted cancer therapies.
• Chemical Biology Probes: Utilized to create tool compounds for investigating biological processes and target validation.
• Fine Chemical Synthesis: Acts as a specialized reagent for constructing complex molecules in custom synthesis projects.

Basic Information

Product Name	n-[4-({[4-(Aminosulfonyl)Phenyl]Amino}Sulfonyl)Phenyl]-3-Chloro-1-Benzothiophene-2-Carboxamide
CAS No.	444151-61-5
Molecular Formula	C21H16ClN3O5S3
Molecular Weight	530.01 g/mol
Synonyms	3-Chloro-N-[4-({[4-(aminosulfonyl)phenyl]amino}sulfonyl)phenyl]-1-benzothiophene-2-carboxamide; 3-Chloro-1-benzothiophene-2-carboxylic acid [4-({[4-(sulfamoyl)phenyl]amino}sulfonyl)phenyl]amide; 444151-61-5; Benzothiophene-2-carboxamide, N-[4-[[[4-(aminosulfonyl)phenyl]amino]sulfonyl]phenyl]-3-chloro-; N-(4-((4-Sulfamoylphenyl)sulfamoyl)phenyl)-3-chlorobenzo[b]thiophene-2-carboxamide
EINECS	Contact for details

Quality Control

Our n-[4-({[4-(Aminosulfonyl)Phenyl]Amino}Sulfonyl)Phenyl]-3-Chloro-1-Benzothiophene-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided to guarantee batch-to-batch consistency for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.