Description

3-Chloro-6-Methoxy-n-[4-(1-Pyrrolidinylsulfonyl)Phenyl]-1-Benzothiophene-2-Carboxamide is a high-purity, synthetic organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical pharmacological intermediate, particularly valued for its role in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the discovery and production of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates for clinical research.
• Kinase Inhibitor Research: Used in the development and screening of compounds designed to modulate kinase activity for potential oncology and anti-inflammatory applications.
• Chemical Biology Probes: Serves as a core structure for creating specialized probes to study enzyme function and cellular signaling pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Reference Standard: Utilized as an analytical standard for quality control and method development in API (Active Pharmaceutical Ingredient) manufacturing.
• Preclinical Development: Supplies material for early-stage pharmacological and toxicological evaluation of new chemical entities.

Basic Information

Product Name	3-Chloro-6-Methoxy-n-[4-(1-Pyrrolidinylsulfonyl)Phenyl]-1-Benzothiophene-2-Carboxamide
CAS No.	444112-48-5
Molecular Formula	C20H19ClN2O4S2
Molecular Weight	450.96 g/mol
Synonyms	3-Chloro-6-methoxy-N-[4-(pyrrolidine-1-sulfonyl)phenyl]-1-benzothiophene-2-carboxamide; 3-Chloro-6-methoxy-N-(4-(pyrrolidin-1-ylsulfonyl)phenyl)benzo[b]thiophene-2-carboxamide; 3-Chloro-6-methoxy-N-[4-(1-pyrrolidinylsulfonyl)phenyl]-1-benzothiophene-2-carboxamide; 444112-48-5; Benzo[b]thiophene-2-carboxamide, 3-chloro-6-methoxy-N-[4-(1-pyrrolidinylsulfonyl)phenyl]-; TAK-285 Intermediate; Kinase Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment. We support development and cGMP-grade production to meet the exacting requirements of pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be stored away from light. Keep container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.