Description

2-Hydroxy-3-(Trimethylsilyl)Benzaldehyde is a specialized organosilicon derivative of salicylaldehyde, featuring a trimethylsilyl (TMS) group ortho to the formyl functionality. This compound is valued as a versatile building block in advanced organic synthesis, particularly for constructing complex molecular architectures where steric protection and silicon-based directing effects are beneficial. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those requiring silicon-containing bioactive molecules or protected phenolic aldehydes.
• Ligand Synthesis: Used to prepare sophisticated chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a building block for developing new pesticides and herbicides with enhanced stability and efficacy.
• Material Science: Employed in the creation of specialty monomers for silicon-modified polymers, resins, and advanced coatings.
• Organic Synthesis Reagent: Functions as a protected and sterically hindered aldehyde component in multi-step reactions like condensations and cyclizations.

Basic Information

Product Name	2-Hydroxy-3-(Trimethylsilyl)Benzaldehyde
CAS No.	444095-29-8
Molecular Formula	C₁₁H₁₆O₂Si
Molecular Weight	208.33 g/mol
Synonyms	3-(Trimethylsilyl)salicylaldehyde; 2-Formyl-6-(trimethylsilyl)phenol; Salicylaldehyde, 3-(trimethylsilyl)-; 2-Hydroxy-3-trimethylsilylbenzaldehyde; TMS-Salicylaldehyde; 3-TMS-Salicylaldehyde; o-Hydroxy-m-trimethylsilylbenzaldehyde
EINECS	Contact for details

Quality Control

Our production of 2-Hydroxy-3-(Trimethylsilyl)Benzaldehyde adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.