Description

Bicyclo[3.2.0]Heptane-3-Acetic Acid, 3-(Aminomethyl)-, Methyl Ester, (1-α-,3-α-,5-α-)- (9Ci) is a high-purity, functionalized bicyclic compound that serves as a critical chiral building block in advanced organic synthesis. Its unique fused-ring structure with both ester and aminomethyl functional groups makes it a versatile intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its bicyclic scaffold contributes to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of complex fragrance molecules, flavors, and other specialty chemicals requiring high stereochemical purity.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry, including ring-opening reactions and functional group transformations.
• Peptidomimetic Research: The aminomethyl group allows for incorporation into peptide backbones to create conformationally restricted analogs for drug discovery.

Basic Information

Product Name	Bicyclo[3.2.0]Heptane-3-Acetic Acid, 3-(Aminomethyl)-, Methyl Ester, (1-α-,3-α-,5-α-)- (9Ci)
CAS No.	444088-20-4
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	(1α,3α,5α)-3-(Aminomethyl)bicyclo[3.2.0]heptane-3-acetic acid methyl ester; Methyl (1α,3α,5α)-3-(aminomethyl)bicyclo[3.2.0]heptane-3-acetate; Bicyclo[3.2.0]heptane-3-acetic acid, 3-(aminomethyl)-, methyl ester, (1α,3α,5α)-; 3-(Aminomethyl)-3-(methoxycarbonylmethyl)bicyclo[3.2.0]heptane; (1R,3S,5R)-3-(Aminomethyl)bicyclo[3.2.0]heptane-3-acetic acid methyl ester; Methyl 3-(aminomethyl)bicyclo[3.2.0]heptane-3-acetate; 444088-20-4; Aminomethyl bicycloheptane acetate methyl ester
EINECS	Contact for details

Quality Control

Our production of Bicyclo[3.2.0]Heptane-3-Acetic Acid, 3-(Aminomethyl)-, Methyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture uptake and oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.