Description

2H-1-Benzopyran-2-One,7,8-Dihydroxy-4-(Hydroxymethyl)-(9Ci) is a specialized, multi-functional coumarin derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound's unique structure, featuring a hydroxymethyl group and catechol moiety, makes it a valuable key intermediate for developing novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring precise molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly those targeting oxidative stress-related pathways or requiring specific metal-chelating properties.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the coumarin core can contribute to specific biological activity.
• Fine Chemical Synthesis: Acts as a versatile precursor for synthesizing complex natural product analogs, flavors, and fragrances.
• Material Science: Investigated for use in organic electronic materials and as a ligand for metal-organic frameworks (MOFs) due to its hydroxyl functional groups.
• Biochemical Research: Employed in studies related to enzyme inhibition, antioxidant activity assays, and as a probe in chemical biology.

Basic Information

Product Name	2H-1-Benzopyran-2-One,7,8-Dihydroxy-4-(Hydroxymethyl)-(9Ci)
CAS No.	443650-48-4
Molecular Formula	C10H8O5
Molecular Weight	208.17 g/mol
Synonyms	4-(Hydroxymethyl)-7,8-dihydroxy-2H-chromen-2-one; 7,8-Dihydroxy-4-(hydroxymethyl)-2H-chromen-2-one; 7,8-Dihydroxy-4-(hydroxymethyl)coumarin; 4-Hydroxymethyl-7,8-dihydroxycoumarin; (7,8-Dihydroxy-2-oxo-2H-chromen-4-yl)methanol; 2H-1-Benzopyran-2-one, 7,8-dihydroxy-4-(hydroxymethyl)-; 9CI Index Name
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with each shipment. We can support development projects with custom purity grades and specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.