Description

tert-Butyl 7-Methyl-1H-Indole-1-Carboxylate is a high-purity, protected indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the indole scaffold's bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, dyes, and photostabilizers due to its conjugated indole system.
• Academic & Contract Research: Essential reagent in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.
• Peptidomimetics Development: Utilized in creating indole-based scaffolds that mimic peptide structures for drug discovery.
• Chemical Biology Probes: Acts as a starting material for synthesizing fluorescent tags or enzyme inhibitors used in biochemical assays.

Basic Information

Product Name	tert-Butyl 7-Methyl-1H-Indole-1-Carboxylate
CAS No.	442910-62-5
Molecular Formula	C14H17NO2
Molecular Weight	231.29 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 7-methyl-, 1,1-dimethylethyl ester; 7-Methyl-1H-indole-1-carboxylic acid tert-butyl ester; tert-Butyl 7-methylindole-1-carboxylate; 1-Boc-7-methylindole; 7-Methyl-1-Boc-indole; 442910-62-5; 7-Methylindole-1-carboxylic acid tert-butyl ester; tert-Butyl 7-methyl-1H-indole-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Methyl-1H-Indole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for advanced intermediates and can tailor purity grades to meet specific project requirements, from research (≥95%) to process development (≥98%) grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.