Description

3-(4-Methoxyphenyl)-2-Methyl-1-Oxo-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex tetrahydroisoquinoline-based molecular libraries.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	3-(4-Methoxyphenyl)-2-Methyl-1-Oxo-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid
CAS No.	442858-64-2
Molecular Formula	C19H17NO4
Molecular Weight	323.34 g/mol
Synonyms	4-Carboxy-3-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-one; 1,2,3,4-Tetrahydro-3-(4-methoxyphenyl)-2-methyl-1-oxo-4-isoquinolinecarboxylic acid; 3-(4-Methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydro-4-isoquinolinecarboxylic acid; Tetrahydroisoquinoline-4-carboxylic acid derivative; 442858-64-2; 3-(p-Methoxyphenyl)-2-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-(4-Methoxyphenyl)-2-Methyl-1-Oxo-1,2,3,4-Tetrahydroisoquinoline-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.