Description

cis-5-({[1-(4-Chlorophenyl)-1H-Tetraazol-5-Yl]Sulfanyl}Acetyl)-2,8-Dimethyl-2,3,4,4A,5,9B-Hexahydro-1H-Pyrido[4,3-B]Indole is a high-purity, complex heterocyclic organic compound featuring a fused pyridoindole core linked to a chlorophenyltetrazole moiety via a thioacetyl bridge. This compound matters as a sophisticated pharmaceutical intermediate or research chemical critical for the development of novel bioactive molecules, particularly in central nervous system (CNS) and receptor-targeted therapies. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting serotonin, dopamine, or other neurotransmitter receptors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Biochemical Probe Development: Serves as a precursor for labeled compounds used in binding assays and pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs for scale-up synthesis under cGMP conditions for preclinical and clinical trial material.
• Academic Research: Utilized in university laboratories for investigating new synthetic methodologies and heterocyclic chemistry.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Item	Detail
Product Name	cis-5-({[1-(4-Chlorophenyl)-1H-Tetraazol-5-Yl]Sulfanyl}Acetyl)-2,8-Dimethyl-2,3,4,4A,5,9B-Hexahydro-1H-Pyrido[4,3-B]Indole
CAS No.	442656-02-2
Molecular Formula	C22H23ClN6OS
Molecular Weight	454.97 g/mol
Synonyms	cis-5-[(1-(4-Chlorophenyl)-1H-tetrazol-5-ylthio)acetyl]-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole; 442656-02-2; UNII-9J4865I39V; 1H-Pyrido[4,3-b]indole, cis-5-[2-[1-(4-chlorophenyl)-1H-tetrazol-5-yl]thio]acetyl]-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-; 9J4865I39V; cis-5-({[1-(4-Chlorophenyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole; BDBM50191057; AKOS005715890
EINECS	Contact for details

Quality Control

Our cis-5-({[1-(4-Chlorophenyl)-1H-Tetraazol-5-Yl]Sulfanyl}Acetyl)-2,8-Dimethyl-2,3,4,4A,5,9B-Hexahydro-1H-Pyrido[4,3-B]Indole is manufactured under strict quality management systems. Products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing all critical parameters. Our quality commitment aligns with ISO 9001 standards, and we can support development under cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C (59-77°F), in a cool, dry, and well-ventilated area. Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.