Description

Diethyl-D10 Carbonate is a deuterated analog of diethyl carbonate, where all hydrogen atoms are replaced with deuterium (D), a stable hydrogen isotope. This high isotopic purity makes it an invaluable non-radioactive tracer and labeling reagent in advanced analytical and synthetic chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for mechanistic studies, metabolic pathway tracing, and the synthesis of deuterated compounds for NMR spectroscopy and mass spectrometry.

Application

• NMR Spectroscopy Solvent & Internal Standard: Used as a deuterated solvent or chemical shift reference in nuclear magnetic resonance (NMR) analysis due to its specific spectral properties.
• Isotopic Labeling in Pharmaceutical R&D: Serves as a key building block for synthesizing deuterium-labeled drug candidates to study pharmacokinetics, metabolism, and bioavailability.
• Mass Spectrometry Tracer: Employed as an internal standard in quantitative LC-MS and GC-MS methods for accurate biomolecule quantification and metabolic flux analysis.
• Deuterated Polymer & Material Synthesis: Used in the production of specialty polymers and organic electronic materials where deuterium substitution can alter physical properties like stability and conductivity.
• Mechanistic Reaction Studies: Acts as a probe in organic reaction mechanisms to trace hydrogen/deuterium exchange pathways and intermediate structures.
• Agrochemical Research: Utilized in the development and environmental fate studies of deuterated pesticides and herbicides.

Basic Information

Product Name	Diethyl-D10 Carbonate
CAS No.	440671-47-6
Molecular Formula	C5D10O3
Molecular Weight	128.19 g/mol (deuterated form)
Synonyms	Diethyl Carbonate-d10; DEC-d10; Diethyl-d10 Carbonate; Ethyl Carbonate-d10; Carbonic Acid Diethyl-d10 Ester; Diethyl [²H₁₀]carbonate; (OCD3CD2)2CO; Diethyl Carbonate (Perdeuterated)
EINECS	Contact for details

Quality Control

Every batch of our Diethyl-D10 Carbonate is produced and analyzed under strict quality protocols to ensure exceptional isotopic and chemical purity, critical for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (typically ≥99 atom % D), chemical purity by GC/HPLC, and identity confirmation by NMR and IR. Our quality system supports compliance with the stringent requirements of GMP/GLP environments for advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright away from heat sources and open flames. Keep under an inert atmosphere if prolonged storage is required to maintain isotopic purity.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Isotopic Purity (Atom % D)	≥ 99.0%
Chemical Purity (GC)	≥ 99.5%
Water Content (KF)	≤ 0.05%
Residue on Evaporation	≤ 0.01%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.