Description

4-Chloro-6-Isopropyl-Thieno[2,3-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 439692-52-1. This heterocyclic compound is a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is essential for research institutions and manufacturers in the pharmaceutical and agrochemical industries developing novel small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents for oncology and inflammatory diseases.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Synthesis Building Block: Used in organic synthesis to construct complex heterocyclic systems for material science and specialty chemistry applications.
• Biochemical Research: Employed in life science research as a molecular probe or inhibitor to study enzymatic pathways and biological mechanisms.
• API Development: Integral in the research and development (R&D) and scale-up processes for new drug candidates under Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) standards.

Basic Information

Product Name	4-Chloro-6-Isopropyl-Thieno[2,3-D]Pyrimidine
CAS No.	439692-52-1
Molecular Formula	C9H9ClN2S
Molecular Weight	212.70 g/mol
Synonyms	4-Chloro-6-(propan-2-yl)thieno[2,3-d]pyrimidine; 4-Chloro-6-isopropylthieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidine, 4-chloro-6-(1-methylethyl)-; 439692-52-1; 6-Isopropyl-4-chlorothieno[2,3-d]pyrimidine; 4-Chloro-6-(1-methylethyl)thieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-6-Isopropyl-Thieno[2,3-D]Pyrimidine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical R&D and scale-up. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥97% by HPLC), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.