Description

1-[(2-Chloro-1,3-Thiazol-5-Yl)Methyl]-1H-Indole-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole-thiazole hybrid structure. This compound is of significant commercial importance for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of next-generation insecticides and fungicides, leveraging its heterocyclic scaffold.
• Chemical Research: Serves as a versatile building block for medicinal chemistry and process chemistry research in both academic and industrial settings.
• API Development: Integral in the scale-up and process optimization stages for new active pharmaceutical ingredients under clinical investigation.

Basic Information

Product Name	1-[(2-Chloro-1,3-Thiazol-5-Yl)Methyl]-1H-Indole-3-Carbaldehyde
CAS No.	439095-43-9
Molecular Formula	C₁₃H₉ClN₂OS
Molecular Weight	276.74 g/mol
Synonyms	1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-1H-indole-3-carboxaldehyde; 1-[(2-Chlorothiazol-5-yl)methyl]indole-3-carbaldehyde; 1H-Indole-3-carboxaldehyde, 1-[(2-chloro-5-thiazolyl)methyl]-; 439095-43-9; 2-Chloro-5-[(3-formyl-1H-indol-1-yl)methyl]-1,3-thiazole
EINECS	Contact for details

Quality Control

Every batch of 1-[(2-Chloro-1,3-Thiazol-5-Yl)Methyl]-1H-Indole-3-Carbaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical R&D and scale-up. A detailed Certificate of Analysis (COA) with HPLC purity, identity confirmation (IR, NMR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.