Description

1-Methyl-2-Phenethyl-3-(Trifluoromethyl)-3-Indolinol is a specialized indoline derivative of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate or building block in the development of complex, high-value molecules. Pharmaceutical researchers and fine chemical manufacturers need it for applications in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the synthesis of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies in organic synthesis and heterocyclic chemistry.
• Fine Chemical Production: Integrated into multi-step synthetic routes for producing other high-value, complex indoline-based specialty chemicals.

Basic Information

Product Name	1-Methyl-2-Phenethyl-3-(Trifluoromethyl)-3-Indolinol
CAS No.	439095-40-6
Molecular Formula	C18H18F3NO
Molecular Weight	321.34 g/mol
Synonyms	3-Indolinol, 1-methyl-2-(2-phenylethyl)-3-(trifluoromethyl)-; 1-Methyl-2-(2-phenylethyl)-3-(trifluoromethyl)-3-indolinol; 2-Phenethyl-1-methyl-3-(trifluoromethyl)indolin-3-ol; 3-Hydroxy-1-methyl-2-phenethyl-3-(trifluoromethyl)indoline; CAS 439095-40-6
EINECS	Contact for details

Quality Control

Our 1-Methyl-2-Phenethyl-3-(Trifluoromethyl)-3-Indolinol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality system is designed to meet the stringent requirements of research and development as well as scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.