Description

2-Phenoxyethyl-2,2-D2 Alcohol is a selectively deuterated derivative of 2-phenoxyethanol, where two hydrogen atoms at the 2-position are replaced with deuterium (D). This isotopic labeling makes it a crucial building block for the synthesis of deuterated compounds used in advanced research and analytical applications. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require isotopically labeled intermediates for metabolic studies, NMR spectroscopy, and the development of compounds with modified stability and pharmacokinetic properties.

Application

• Pharmaceutical Research: As a deuterated synthon for creating Active Pharmaceutical Ingredients (APIs) with deuterium incorporation, used in drug discovery and development for metabolic stability studies and as potential deuterated drugs.
• Analytical Chemistry: Serving as an internal standard or reference material in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy due to its distinct isotopic signature.
• Agrochemical Development: Used in the synthesis of deuterated pesticides or herbicides to study environmental fate, metabolic pathways, and to potentially enhance product performance.
• Material Science: A precursor for synthesizing deuterated polymers, liquid crystals, or other advanced materials where isotopic substitution can alter physical properties like thermal stability or optical characteristics.
• Mechanistic Studies: Employed in kinetic isotope effect (KIE) studies to investigate reaction mechanisms and pathways in organic and catalytic chemistry.

Basic Information

Product Name	2-Phenoxyethyl-2,2-D2 Alcohol
CAS No.	438620-17-8
Molecular Formula	C8H8D2O2
Molecular Weight	140.19 g/mol (approx.)
Synonyms	2,2-Dideutero-2-phenoxyethanol; 2-Phenoxyethanol-2,2-d2; Deutero-2-phenoxyethanol; (2,2-Dideuteroethoxy)benzene; Ethylene glycol-1,1-d2 monophenyl ether; Phenoxyethyl-d2 alcohol; β,β-Dideuterophenoxyethanol; 1-Phenoxy-2,2-dideuteroethan-2-ol
EINECS	Contact for details

Quality Control

Our 2-Phenoxyethyl-2,2-D2 Alcohol is produced under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of research and development. Each batch undergoes rigorous analytical testing, including NMR and GC-MS or HPLC, to confirm deuterium incorporation, chemical identity, and purity. Certificates of Analysis (COA) detailing isotopic enrichment and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC / GC)	≥ 95%
Isotopic Enrichment (D, NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.