Description

Ethyl 5-Amino-4-(Aminocarbonyl)-3-Methyl-2-Thiophenecarboxylate is a high-purity, multi-functional thiophene derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of complex heterocyclic molecules, particularly in pharmaceutical and agrochemical research. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its thiophene core.
• Dye & Pigment Industry: Intermediate for synthesizing specialized heterocyclic dyes and pigments with unique colorfastness and light-absorption properties.
• Academic & Contract Research: Essential reagent for methodological development in organic chemistry and for producing custom compounds in contract research organizations (CROs).
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and diagnostic agents used in biochemical assays and imaging.

Basic Information

Product Name	Ethyl 5-Amino-4-(Aminocarbonyl)-3-Methyl-2-Thiophenecarboxylate
CAS No.	438531-05-6
Molecular Formula	C9H12N2O3S
Molecular Weight	228.27 g/mol
Synonyms	Ethyl 5-Amino-4-carbamoyl-3-methylthiophene-2-carboxylate; 5-Amino-4-carbamoyl-3-methyl-2-thiophenecarboxylic Acid Ethyl Ester; 2-Thiophenecarboxylic acid, 5-amino-4-(aminocarbonyl)-3-methyl-, ethyl ester; Ethyl 5-amino-3-methyl-4-(aminocarbonyl)thiophene-2-carboxylate; 438531-05-6; AKOS BRN 0972; CTK8G0335; NSC 796093; ZINC000004018756
EINECS	Contact for details

Quality Control

Our Ethyl 5-Amino-4-(Aminocarbonyl)-3-Methyl-2-Thiophenecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality supports compliance with cGMP guidelines where applicable for pharmaceutical intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.