Description

2-Bromo-5-(cyclopentylsulfonyl)thiophene is a high-value, functionalized thiophene derivative characterized by its bromine and sulfone substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. It is primarily utilized by research institutions and industrial manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used as a building block for developing novel pesticides, herbicides, and fungicides due to its bioactive thiophene core.
• Material Science: Serves as a precursor for organic electronic materials, such as conductive polymers and semiconductors, leveraging the thiophene moiety.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) where the bromine atom acts as a handle for further functionalization.
• Ligand & Catalyst Development: Utilized in the design of novel ligands and organocatalysts for asymmetric synthesis.
• Life Science Research: Acts as a biochemical probe or a standard in analytical method development for pharmacokinetic studies.

Basic Information

Product Name	2-Bromo-5-(cyclopentylsulfonyl)thiophene
CAS No.	438234-34-5
Molecular Formula	C9H11BrO2S2
Molecular Weight	295.22 g/mol
Synonyms	2-Bromo-5-cyclopentylsulfonylthiophene; Thiophene, 2-bromo-5-(cyclopentylsulfonyl)-; 5-(Cyclopentylsulfonyl)-2-bromothiophene; 2-Bromo-5-(cyclopentanesulfonyl)thiophene; 2-Bromothiophene-5-sulfonic acid cyclopentyl ester; Cyclopentyl 2-bromothiophene-5-sulfonate; 438234-34-5
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(cyclopentylsulfonyl)thiophene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.