Description

2-Amino-6-tert-Butyl-Benzo[B]Thiophene-3-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both amino and ester functionalities on a benzo[b]thiophene core, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel herbicides, fungicides, and insecticides with potentially improved efficacy and environmental profiles.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and advanced polymers due to its electron-rich thiophene structure.
• Dye & Pigment Chemistry: Acts as a precursor for synthesizing specialized heterocyclic dyes and pigments with specific light-absorption properties.
• Academic & Contract Research: An essential reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	2-Amino-6-tert-Butyl-Benzo[B]Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	438228-39-8
Molecular Formula	C15H19NO2S
Molecular Weight	277.38 g/mol
Synonyms	Ethyl 2-Amino-6-tert-butyl-1-benzothiophene-3-carboxylate; 6-tert-Butyl-2-amino-1-benzothiophene-3-carboxylic acid ethyl ester; 2-Amino-6-(tert-butyl)benzo[b]thiophene-3-carboxylic acid ethyl ester; 2-Amino-6-tert-butylbenzo[b]thiophene-3-carboxylic acid ethyl ester; 438228-39-8; Ethyl 2-amino-6-(tert-butyl)benzo[b]thiophene-3-carboxylate; 6-tert-Butyl-2-aminobenzo[b]thiophene-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 2-Amino-6-tert-Butyl-Benzo[B]Thiophene-3-Carboxylic Acid Ethyl Ester adheres to stringent in-process controls and final batch testing to ensure consistent high purity and chemical identity. We employ advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for identity, purity, and impurity profiles. Our quality management system is designed to support cGMP (current Good Manufacturing Practice) standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.