Description

2-Amino-4-(4-Isobutylphenyl)Thiophene-3-Carbonitrile is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile molecular scaffold, which is designed for the efficient construction of complex pharmacophores and functional materials. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation and central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its thiophene core for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Chemical Synthesis: An essential reagent for constructing complex heterocyclic systems via cyclization and coupling reactions.
• Academic & Contract Research: Employed in universities and CROs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	2-Amino-4-(4-Isobutylphenyl)Thiophene-3-Carbonitrile
CAS No.	438218-65-6
Molecular Formula	C15H16N2S
Molecular Weight	256.37 g/mol
Synonyms	2-Amino-4-(4-isobutylphenyl)thiophene-3-carbonitrile; 4-(4-Isobutylphenyl)-2-aminothiophene-3-carbonitrile; 2-Amino-4-(4-isobutylphenyl)-3-cyanothiophene; 3-Cyano-2-amino-4-(4-isobutylphenyl)thiophene; Thiophene-3-carbonitrile, 2-amino-4-[4-(2-methylpropyl)phenyl]-; 438218-65-6; AI3-52362
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Isobutylphenyl)Thiophene-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.