Description

Isopropyl 2-Amino-6-Phenyl-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique tetrahydrobenzothiophene core structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and serves as a versatile building block in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic molecules.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for complex, high-value APIs.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring a functionalized benzothiophene scaffold.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and process development projects.

Basic Information

Item	Details
Product Name	Isopropyl 2-Amino-6-Phenyl-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate
CAS No.	438214-76-7
Molecular Formula	C18H21NO2S
Molecular Weight	315.43 g/mol
Synonyms	2-Amino-6-phenyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid isopropyl ester; Isopropyl 2-amino-6-phenyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate; 438214-76-7; Tetrahydrobenzothiophene carboxylate derivative; 6-Phenyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid, 2-amino-, 1-methylethyl ester
EINECS	Contact for details

Quality Control

Our Isopropyl 2-Amino-6-Phenyl-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.