Description

1H-Indazole,4,5,6,7-Tetrahydro-7-(1-Methylethyl)-,(7R)-(9Ci) is a chiral, saturated indazole derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and pharmacophore for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its saturated, chiral indazole structure.
• Asymmetric Synthesis: Employed as a chiral ligand precursor or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Fine Chemical Production: Serves as a building block for the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemistry.
• Biochemical Tool Compound: Potential use in developing probes for studying enzyme mechanisms or biological pathways where the indazole motif is relevant.

Basic Information

Product Name	1H-Indazole,4,5,6,7-Tetrahydro-7-(1-Methylethyl)-,(7R)-(9Ci)
CAS No.	437650-77-6
Molecular Formula	C10H16N2
Molecular Weight	164.25 g/mol
Synonyms	(7R)-7-Isopropyl-4,5,6,7-tetrahydro-1H-indazole; (R)-7-Isopropyl-4,5,6,7-tetrahydro-1H-indazole; 4,5,6,7-Tetrahydro-7-(1-methylethyl)-1H-indazole, (7R)-; 7-Isopropyl-4,5,6,7-tetrahydro-1H-indazole (enantiomer); SCHEMBL2188307; A1-00826; AKOS040759395; ZINC000004169756
EINECS	Contact for details

Quality Control

Our 1H-Indazole,4,5,6,7-Tetrahydro-7-(1-Methylethyl)-,(7R)-(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and enantiomeric purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.