Description

4-(3-Trifluoromethoxy-Phenyl)-Thiazol-2-Ylamine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct thiazole core and trifluoromethoxy-substituted aromatic ring. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the thiazole moiety.
• Material Science: Used in the development of specialty chemicals, including advanced polymers and liquid crystals, where its aromatic and heterocyclic structure imparts specific electronic properties.
• Chemical Synthesis: Acts as a versatile reagent for constructing complex heterocyclic systems in academic and industrial organic chemistry laboratories.

Basic Information

Product Name	4-(3-Trifluoromethoxy-Phenyl)-Thiazol-2-Ylamine
CAS No.	436151-97-2
Molecular Formula	C10H7F3N2OS
Molecular Weight	260.24 g/mol
Synonyms	2-Amino-4-[3-(trifluoromethoxy)phenyl]-1,3-thiazole; 4-(3-Trifluoromethoxyphenyl)-2-aminothiazole; 2-Thiazolamine, 4-[3-(trifluoromethoxy)phenyl]-; 4-(3-(Trifluoromethoxy)phenyl)thiazol-2-amine; 4-(α,α,α-Trifluoro-m-tolyloxy)-2-aminothiazole
EINECS	Contact for details

Quality Control

Our 4-(3-Trifluoromethoxy-Phenyl)-Thiazol-2-Ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.