Description

5-(4-Amino-Phenylcarbamoyl)-3H-Imidazole-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct imidazole-carboxylic acid core structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing new therapeutic agents, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting specific enzyme inhibitors.
• Medicinal Chemistry Research: Used as a versatile building block for constructing complex molecular libraries in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialized agrochemicals and high-value specialty chemicals.
• Bioconjugation & Probe Development: The reactive amine and carboxylic acid groups make it suitable for developing biochemical probes and diagnostic agents.
• Academic & Industrial R&D: Fundamental research into new heterocyclic compounds and their biological activities.

Basic Information

Product Name	5-(4-Amino-Phenylcarbamoyl)-3H-Imidazole-4-Carboxylic Acid
CAS No.	436088-52-7
Molecular Formula	C11H10N4O3
Molecular Weight	246.22 g/mol
Synonyms	4-Carboxy-5-[(4-aminophenyl)carbamoyl]-1H-imidazole; 1H-Imidazole-4-carboxylic acid, 5-[(4-aminophenyl)amino]carbonyl]-; 5-[(4-Aminophenyl)carbamoyl]-1H-imidazole-4-carboxylic acid; 5-(4-Aminobenzamido)-1H-imidazole-4-carboxylic acid; 436088-52-7; 5-(4-Amino-phenylcarbamoyl)-3H-imidazol-4-carboxylic acid; 5-(4-Aminophenylcarbamoyl)imidazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(4-Amino-Phenylcarbamoyl)-3H-Imidazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.