Description

1-(2-Azepan-1-Yl-2-Oxo-Ethyl)-1H-Indole-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate featuring a unique indole-azepane hybrid structure. This compound matters for its critical role as a sophisticated building block in the synthesis of novel bioactive molecules, enabling research and development in targeted therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and academic institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Employed in the development of enzyme inhibitors or receptor modulators for pharmacological research.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Contract Manufacturing: Supplied to CMOs for the cGMP production of active pharmaceutical ingredients (APIs) at various development stages.

Basic Information

Product Name	1-(2-Azepan-1-Yl-2-Oxo-Ethyl)-1H-Indole-3-Carbaldehyde
CAS No.	436087-09-1
Molecular Formula	C17H20N2O2
Molecular Weight	284.35 g/mol
Synonyms	1H-Indole-3-carboxaldehyde, 1-[2-(1-azepanyl)-2-oxoethyl]-; 1-(2-Oxo-2-azepan-1-ylethyl)-1H-indole-3-carbaldehyde; 1-(2-(Azepan-1-yl)-2-oxoethyl)-1H-indole-3-carbaldehyde; 1-(2-Azepan-1-yl-2-oxoethyl)indole-3-carboxaldehyde; 436087-09-1; 1-(2-(1-Azepanyl)-2-oxoethyl)-1H-indole-3-carboxaldehyde; 1-(2-(Hexahydro-1H-azepin-1-yl)-2-oxoethyl)-1H-indole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-(2-Azepan-1-Yl-2-Oxo-Ethyl)-1H-Indole-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports development from research to commercial scale, with documentation tailored to meet the requirements of cGMP, ICH guidelines, and relevant pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.