Description

5-Bromo-6-Fluoro-1H-Indole is a high-purity halogenated indole derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both bromine and fluorine substituents, makes it an exceptionally versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and receptor modulator research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the halogenated indole core.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLEDs and conductive polymers, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags and molecular probes for studying biological processes.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	5-Bromo-6-Fluoro-1H-Indole
CAS No.	434960-42-6
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	5-Bromo-6-fluoroindole; 6-Fluoro-5-bromo-1H-indole; 1H-Indole, 5-bromo-6-fluoro-; 5-Bromo-6-fluoro-1H-indole; 434960-42-6; 5-Br-6-F-indole
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-6-Fluoro-1H-Indole adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, GC-MS, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality system is designed to meet the exacting standards required for pharmaceutical R&D and other high-value applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Purity (HPLC Area %)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.