Description

1-Boc-5-Hydroxyindole is a protected indole derivative of significant importance in advanced organic synthesis. This compound serves as a versatile and critical building block for the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and combinatorial chemistry libraries due to its protected functional groups.
• Peptidomimetic Synthesis: Serves as a scaffold for creating indole-based peptidomimetics and protease inhibitors.
• Agrochemical Development: Employed in the research and synthesis of new herbicides and plant growth regulators.
• Material Science: Potential building block for organic electronic materials and advanced polymers.
• Academic & Contract Research: Essential reagent in university laboratories and CROs (Contract Research Organizations) for exploratory organic synthesis.

Basic Information

Product Name	1-Boc-5-Hydroxyindole
CAS No.	434958-85-7
Molecular Formula	C₁₃H₁₅NO₃
Molecular Weight	233.26 g/mol
Synonyms	5-Hydroxy-1H-indole-1-carboxylic acid, 1,1-dimethylethyl ester; tert-Butyl 5-hydroxy-1H-indole-1-carboxylate; 5-Hydroxyindole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-5-hydroxyindole; N-Boc-5-hydroxyindole; Boc-5-OH-indole; 1-Boc-5-indolol
EINECS	Contact for details

Quality Control

Our 1-Boc-5-Hydroxyindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.