Description

2,6-Piperazinedione,3-Methyl-,(3R)-(9Ci) is a chiral piperazinedione derivative, a high-value synthetic intermediate of significant interest in advanced organic synthesis. Its stereochemically defined structure makes it a critical building block for the development of novel pharmaceutical compounds and bioactive molecules. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate complex heterocyclic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used as a precursor in the synthesis of advanced, stereoselective herbicides, fungicides, and plant growth regulators.
• Fine Chemical Building Block: Employed in the construction of complex natural product analogs, macrocycles, and other specialty chemicals requiring a rigid, functionalized diketopiperazine core.
• Bioconjugation & Peptidomimetics: Serves as a constrained scaffold in the design of peptidomimetics and bioconjugation linkers to improve metabolic stability and binding affinity.
• Academic & Contract Research: A valuable reagent for academic institutions and CROs (Contract Research Organizations) exploring novel heterocyclic chemistry and medicinal chemistry programs.
• Catalyst & Ligand Development: Potential precursor for the synthesis of chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2,6-Piperazinedione,3-Methyl-,(3R)-(9Ci)
CAS No.	434314-23-5
Molecular Formula	C5H8N2O2
Molecular Weight	128.13 g/mol
Synonyms	(3R)-3-Methylpiperazine-2,6-dione; (R)-3-Methyl-2,6-piperazinedione; (R)-3-Methylpiperazine-2,6-dione; 3-Methyl-2,6-piperazinedione, (R)-; (R)-3-Methyl-2,6-diketopiperazine; (R)-3-Methyl-DKP; (3R)-3-Methyl-2,6-dioxopiperazine; (R)-3-Methyl-2,6-dioxopiperazine
EINECS	Contact for details

Quality Control

Our 2,6-Piperazinedione,3-Methyl-,(3R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.