Description

n-(4-Ethoxyphenyl)-2-[2-(Trifluoromethyl)-1H-1,3-Benzimidazol-1-Yl]Acetamide is a specialized benzimidazole derivative, a high-value chemical intermediate prized for its unique trifluoromethyl-substituted heterocyclic structure. This compound is critical for research and development in advanced material science and pharmaceutical chemistry, offering a versatile scaffold for creating novel molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Acts as a monomer or functional additive in the creation of advanced polymers, liquid crystals, or organic electronic materials.
• Biochemical Tool Compound: Employed in life science research as a probe or inhibitor to study specific enzymatic pathways or protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	n-(4-Ethoxyphenyl)-2-[2-(Trifluoromethyl)-1H-1,3-Benzimidazol-1-Yl]Acetamide
CAS No.	433252-86-9
Molecular Formula	C18H16F3N3O2
Molecular Weight	363.34 g/mol
Synonyms	N-(4-Ethoxyphenyl)-2-[2-(trifluoromethyl)-1H-benzimidazol-1-yl]acetamide; 2-[2-(Trifluoromethyl)-1H-benzimidazol-1-yl]-N-(4-ethoxyphenyl)acetamide; 1H-Benzimidazole-1-acetamide, N-(4-ethoxyphenyl)-2-(trifluoromethyl)-; Acetamide, N-(4-ethoxyphenyl)-2-[2-(trifluoromethyl)-1H-benzimidazol-1-yl]-; 433252-86-9; TFMA-Benzimidazole Derivative
EINECS	Contact for details

Quality Control

Our production of n-(4-Ethoxyphenyl)-2-[2-(trifluoromethyl)-1H-1,3-Benzimidazol-1-Yl]Acetamide adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or manufacturing specifications. Our quality systems are designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.