Description

(2-Chloroquinolin-4-Yl)Methanol is a versatile quinoline derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized quinoline-based dyes and colorants.
• Academic and Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	(2-Chloroquinolin-4-Yl)Methanol
CAS No.	432518-08-6
Molecular Formula	C₁₀H₈ClNO
Molecular Weight	193.63 g/mol
Synonyms	4-(Hydroxymethyl)-2-chloroquinoline; 2-Chloro-4-quinolinemethanol; (2-Chloro-4-quinolinyl)methanol; 2-Chloroquinoline-4-methanol; 2-Chloro-4-(hydroxymethyl)quinoline; 4-(Hydroxymethyl)-2-chloro-quinoline; (2-Chloro-quinolin-4-yl)-methanol
EINECS	Contact for details

Quality Control

Our (2-Chloroquinolin-4-Yl)Methanol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.