Description

2-Thiophenecarboxylicacid,Tetrahydro-,Methylester,(2R)-(9Ci) is a high-purity, single-enantiomer chiral building block of significant value in advanced organic synthesis. This compound matters because its stereochemically defined tetrahydrothiophene scaffold serves as a critical intermediate for constructing complex molecules with precise three-dimensional architecture. Pharmaceutical, agrochemical, and specialty chemical R&D teams need it for developing novel active ingredients, particularly where the (2R) configuration is essential for biological activity or material properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral therapeutics.
• Agrochemical Synthesis: Used in creating advanced, enantiomerically pure pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel chiral polymers and functional materials with specific optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for synthetic chemists in universities and corporate labs exploring new reaction methodologies and complex natural product synthesis.

Basic Information

Product Name	2-Thiophenecarboxylicacid,Tetrahydro-,Methylester,(2R)-(9Ci)
CAS No.	432025-73-5
Molecular Formula	C7H10O2S
Molecular Weight	158.22 g/mol
Synonyms	(2R)-Tetrahydro-2-thiophenecarboxylic acid methyl ester; Methyl (2R)-tetrahydrothiophene-2-carboxylate; (R)-Tetrahydrothiophene-2-carboxylic acid methyl ester; (R)-Methyl tetrahydrothiophene-2-carboxylate; (2R)-Tetrahydrothiophene-2-carboxylic Acid Methyl Ester; (R)-THF-2-Carboxylic Acid Methyl Ester; Tetrahydro-2-thiophenecarboxylic acid, methyl ester, (2R)-; (2R)-Methyl tetrahydro-2-thiophenecarboxylate
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including chiral HPLC, GC, and NMR to ensure high enantiomeric excess (ee) and chemical purity suitable for sensitive synthetic applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.