Description

Cyclopenta[B]Pyrrole, 3,3A,4,5,6,6A-Hexahydro-2-(4-Methylphenyl)-, (3Ar,6Ar)- (9Ci) is a complex, stereochemically defined heterocyclic compound that serves as a valuable synthetic intermediate and building block in advanced organic chemistry. Its unique fused-ring structure with a p-tolyl substituent makes it a critical precursor for the development of novel pharmaceuticals and functional materials. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries engaged in the synthesis of complex molecules, where precise stereochemistry and functional group compatibility are paramount.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Research: Used in the discovery and synthesis of novel pesticides and herbicides, leveraging its complex polycyclic structure.
• Material Science: Serves as a precursor for organic electronic materials, including charge-transport layers and light-emitting components, due to its conjugated pyrrole moiety.
• Catalyst Ligand Synthesis: Employed in the preparation of sophisticated chiral ligands for asymmetric catalysis.
• Academic & R&D: A valuable tool for synthetic methodology development and the exploration of new chemical space in medicinal chemistry programs.
• Fine Chemical Production: Used in the multi-step synthesis of high-value specialty chemicals and dyes.

Basic Information

Product Name	Cyclopenta[B]Pyrrole, 3,3A,4,5,6,6A-Hexahydro-2-(4-Methylphenyl)-, (3Ar,6Ar)- (9Ci)
CAS No.	431887-25-1
Molecular Formula	C14H17N
Molecular Weight	199.29 g/mol
Synonyms	(3aR,6aR)-2-(4-Methylphenyl)-3a,4,5,6,6a,7-hexahydro-1H-cyclopenta[b]pyrrole; 2-(4-Methylphenyl)octahydrocyclopenta[b]pyrrole (stereoisomer); Hexahydro-2-(4-methylphenyl)cyclopenta[b]pyrrole; 431887-25-1; Cyclopentapyrrole derivative; p-Tolyl-substituted hexahydrocyclopenta[b]pyrrole; Chiral cyclopenta[b]pyrrole building block.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We operate under a quality management system and can support development projects requiring compliance with cGMP or other regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.