Description

3-(Phenylmethoxy)Benzenethiol is a specialized aromatic thiol derivative featuring a benzyl-protected phenolic ether group. This compound is valued for its dual functionality, serving as a versatile building block and a sulfur-based nucleophile in advanced organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents. Its unique structure makes it a critical intermediate for introducing sulfur-containing motifs into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those requiring thioether or disulfide linkages.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the thiol group is essential for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of functional polymers and advanced materials with specific sulfur-based properties.
• Chemical Biology Probes: Useful for synthesizing probes and conjugates for studying protein interactions and cellular processes.
• Fine Chemical Production: A versatile intermediate in custom and multi-step synthesis for high-value specialty chemicals.

Basic Information

Product Name	3-(Phenylmethoxy)Benzenethiol
CAS No.	431878-96-5
Molecular Formula	C₁₃H₁₂OS
Molecular Weight	216.30 g/mol
Synonyms	3-(Benzyloxy)benzenethiol; (3-(Benzyloxy)phenyl)methanethiol; 3-Benzyloxybenzenethiol; 3-(Benzyloxy)thiophenol; m-(Phenylmethoxy)benzenethiol; 1-Benzyloxy-3-mercaptobenzene; 3-Mercaptophenyl benzyl ether
EINECS	Contact for details

Quality Control

Our 3-(Phenylmethoxy)Benzenethiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay purity and impurity profiles. We adhere to current Good Manufacturing Practices (cGMP) where applicable to guarantee supply consistency and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Due to its sensitivity, the container should be kept tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.