Description

tert-Butyl 6-Aminoisoquinolin-1-Ylcarbamate is a high-purity, protected amine derivative of the isoquinoline scaffold, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive amine handle that is protected from unwanted side reactions, enabling the precise construction of complex molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Organic Synthesis Building Block: Used in multi-step synthesis for introducing the 6-aminoisoquinoline moiety into larger, more complex molecular architectures.
• Agrochemical Research: Employed in the discovery and synthesis of new herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Potential use in the synthesis of organic ligands for catalysts or functional materials.
• Academic & Contract Research: Serves as a valuable reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	tert-Butyl 6-Aminoisoquinolin-1-Ylcarbamate
CAS No.	431053-36-0
Molecular Formula	C₁₄H₁₇N₃O₂
Molecular Weight	259.31 g/mol
Synonyms	1-Isoquinolinecarboxylic acid, 6-amino-, 1,1-dimethylethyl ester; 6-Aminoisoquinolin-1-yl-carbamic acid tert-butyl ester; tert-Butyl N-(6-aminoisoquinolin-1-yl)carbamate; 1-BOC-6-aminoisoquinoline; BOC-6-Aminoisoquinoline; 6-Amino-1-Boc-isoquinoline; tert-Butyl (6-aminoisoquinolin-1-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Aminoisoquinolin-1-Ylcarbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our clients' regulatory requirements in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.