Description

(R)-Methyl-3-(1-Methyl-1H-Indol-3-Yl)-Phenyl-Propionate is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. Its value lies in its role as a key building block for the development of active pharmaceutical ingredients (APIs) with specific stereochemical requirements. This compound is essential for research and manufacturing organizations in the pharmaceutical and fine chemical industries, particularly those focused on neurology, oncology, and other therapeutic areas requiring complex indole-based molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Asymmetric Synthesis: Used in the development of enantiomerically pure compounds for research and commercial production.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Fine Chemical Production: Employed in the multi-step synthesis of complex organic molecules requiring specific (R)-configuration.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(R)-Methyl-3-(1-Methyl-1H-Indol-3-Yl)-Phenyl-Propionate
CAS No.	429689-18-9
Molecular Formula	C20H21NO2
Molecular Weight	307.39 g/mol
Synonyms	(R)-Methyl 3-(1-Methyl-1H-indol-3-yl)-3-phenylpropanoate; (R)-3-(1-Methyl-1H-indol-3-yl)-3-phenylpropanoic Acid Methyl Ester; Methyl (3R)-3-(1-Methylindol-3-yl)-3-phenylpropanoate; (R)-3-(1-Methylindol-3-yl)-3-phenylpropionic Acid Methyl Ester; (R)-MMIPP; (R)-Methyl 3-(1-Methylindol-3-yl)-3-phenylpropionate
EINECS	Contact for details

Quality Control

Our (R)-Methyl-3-(1-Methyl-1H-Indol-3-Yl)-Phenyl-Propionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.