Description

m-Xylene-D4 (Ring-D4) is a deuterated isotopologue of m-xylene, where the four hydrogen atoms on the aromatic ring are replaced with deuterium (CAS NO 425420-97-9). This isotopic labeling is critical for applications requiring non-interfering internal standards in mass spectrometry and for mechanistic studies in NMR spectroscopy. It is an essential reagent for analytical chemists and researchers in the pharmaceutical, agrochemical, and material science industries who require high isotopic purity and chemical stability for precise quantitative analysis and reaction pathway elucidation.

Application

• Internal Standard for GC-MS and LC-MS analysis of xylene isomers and related aromatic compounds.
• NMR Solvent and tracer for studying reaction mechanisms, molecular dynamics, and structural analysis.
• Pharmaceutical Research for drug metabolism and pharmacokinetics (DMPK) studies using isotope dilution methods.
• Polymer and Material Science as a probe for studying diffusion, permeability, and degradation processes in polymers.
• Environmental Analysis as a labeled standard for the detection and quantification of xylene contaminants in complex matrices.
• Organic Synthesis as a building block for the preparation of other deuterated fine chemicals and specialty materials.

Basic Information

Item	Detail
Product Name	m-Xylene-D4 (Ring-D4)
CAS No.	425420-97-9
Molecular Formula	C8D4H6
Molecular Weight	110.20 g/mol
Synonyms	1,3-Dimethylbenzene-D4; 1,3-Dimethyl-d4-benzene; m-Xylene-d4; meta-Xylene-d4; Deuterated m-Xylene; [D4]-m-Xylene; m-Xylene (ring-D4); Isotopic m-Xylene
EINECS	Contact for details

Quality Control

Our m-Xylene-D4 (Ring-D4) is produced under stringent conditions to ensure exceptional isotopic and chemical purity. Each batch undergoes comprehensive analysis, including NMR and GC-MS, to verify deuterium incorporation and chemical identity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming specifications for isotopic purity, chemical purity, and solvent content. Our quality system is designed to meet the rigorous demands of analytical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (NMR)	Conforms to structure
Isotopic Purity (D)	≥ 99 atom % D
Chemical Purity (GC)	≥ 99.0%
Isomeric Purity (GC)	≥ 99.0% (m-Xylene)
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.